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br Experimental Procedures br Acknowledgments br Introductio
2020-12-31

Experimental Procedures Acknowledgments Introduction Incessant consumption of fossil fuels brings on global energy crisis and serious environmental concerns. Hence, the researchers have paid considerable attention to alternative renewable bioenergy. Microalgae has been considered as potenti
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The preferences for source of FAs
2020-12-31

The preferences for source of FAs for DGAT1 and DGAT2 are related to their membrane topologies, subcellular locations, interactions with other proteins or organelles (discussed in the former section), and their differential expression, substrate specificities, and enzyme kinetics. According to UniPr
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Two key enzymes play important roles in the bioconversion of
2020-12-31

Two key enzymes play important roles in the bioconversion of xylitol from d-arabitol, namely d-arabitol dehydrogenase (ArDH) and NADH-dependent xylitol dehydrogenase (XDH), respectively (Qi et al., 2014). In an earlier study, we developed a high xylitol yield strain by expressing xdh in E. coli BL21
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IGF-1, human recombinant br Conclusion br Limitations br Con
2020-12-31

Conclusion Limitations Conflict of interest Financial disclosure The research was supported by National Institute of Mental Health and Neuro Sciences (NIMHANS)Intramural Research Grant ID NIMH/PROJ-RSM/545/2014-15. India. Acknowledgments Introduction Increased central and peripher
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Regarding the effects of CRF
2020-12-31

Regarding the effects of CRF on anxiety, Sahuque et al. (2006) have demonstrated that this neuropeptide also enhances anxiety when injected into the bed nucleus of the stria terminalis (BNST), a GS1101 structure that has also been related to defensive behavior (Casada and Dafny, 1991, Chen et al.,
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Materials and methods br Results br Discussion Microbial pro
2020-12-31

Materials and methods Results Discussion Microbial production of trans-4Hyp, an added-value amino DMOG for pharmaceuticals, offers significant advantages over conventional chemical extraction in economic and environmental aspects. However the low titer and productivity with the existing tran
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atm kinase inhibitor br Loss of Chk sensitizes
2020-12-31

Loss of Chk 1 sensitizes atm kinase inhibitor to hypoxia/reoxygenation In contrast to Chk 2, studies have identified Chk 1 as being phosphorylated in an ATR-dependent manner at residue serine 345 during hypoxia [18]. More recently, siRNA mediated inhibition of Chk 1 signaling was found to sensit
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br Introduction Breast cancer is the most common cancer in
2020-12-31

Introduction Breast cancer is the most common cancer in women and one of the leading causes of death worldwide. Estrogen receptor alpha (ERα, “wild-type” estrogen receptor), encoded by the estrogen receptor1 (ESR1) gene, is expressed in approximately 70% of all breast cancers. Hormonal therapy h
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DBU br Conclusion In conclusion our
2020-12-31

Conclusion In conclusion, our findings do not suggest that HT is an important determinant of future AD risk and are in line with a recent Cochrane review stating that HT is not indicated for preventing dementia or cognitive decline in postmenopausal women [13]. Contributors Conflict of inte
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Recent studies have reported that miR
2020-12-31

Recent studies have reported that miR-454 plays an important role in various cellular processes and diseases, such as inflammation, infection, osteogenic differentiation, and cancers [25,27,29,30]. Multiple evidence has documented that miR-454 promotes the proliferation, migration and invasion, and
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Laminin 925-933 The importance of EBI for B cell function wa
2020-12-30

The importance of EBI2 for B cell function was first suggested by the dramatic upregulation of this receptor in EBV-transformed Laminin 925-933 and further inferred from its regulation in activated and GC B cells (Birkenbach et al., 1993, Glynne et al., 2000, Shaffer et al., 2000). An involvement o
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Generally glycines and other small residues such as alanine
2020-12-30

Generally, glycines (and other small residues such as alanine) present in a helical GxxxG-motif that are facing the same side of the helix form a uniform surface that enables direct contact with a second helix. Crystal structures of multipass membrane proteins have demonstrated that GxxxG-motifs are
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This hydrophobic biphenyl tail gave
2020-12-30

This hydrophobic biphenyl tail gave good binding affinity for human DHODH enzyme (IC corresponding Epinastine HCl was found to be the main metabolite in human microsomes and it was 100-fold less active against hDHODH than the ester. In an attempt to identify the specific non-covalent binding inter
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Introduction Quassinoids are natural products formed through
2020-12-30

Introduction Quassinoids are natural products formed through the oxidative degradation of triterpene derivatives with anti-inflammatory, antimicrobial, antineoplastic, and antiplasmodial effects (Chakraborty and Pal, 2013; Houël et al., 2013). They are characteristic ingredients of the family Simar
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Previous studies on the chemokines role in
2020-12-30

Previous studies on the chemokines role in depression are not detailed enough, and cannot sufficiently demonstrate even a hypothetical mechanism explaining the differences in levels of particular chemokines and their receptors, in relation to the severity of depression [29], [30]. Previous studies o
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